Fig 1. ALS patients exhibit elevated cell counts of granulocytes, NK cells and T cells.

Major leukocyte populations from 80 ALS patients and 50 healthy volunteers were assessed by flow cytometry. A. Comparisons of granulocytes, NK cells, T cells, CD4⁺ T cells, and CD8⁺ T cells between healthy volunteers (dark circles), and ALS patients (open circles). B. CD3⁺CD56⁺ T cells shown as cell counts (cells/μl), percentage of total T cells, and a representative dot plot. C. Correlations of CD4⁺ T cells and CD4:CD8 ratios are altered in ALS patients. D. NK cells and granulocyte counts inversely correlate with ALSFRS-R score.