Table 1. Baseline characteristics of study population.
Control group | POAG group | P value | |
---|---|---|---|
By subject no. | 7 | 10 | |
Male (n, %) | 3 (42.9) | 7 (70.0) | 0.350* |
Age (yrs) (median[25,75 percentile]) | 30 (30, 40) | 67 (56, 72) | <0.001† |
By Eye no. | 10 | 13 | |
Spherical equivalent error (D) | -1.4±1.5 | -1.9±3.3 | 0.685‡ |
IOP (mmHg) | 14.3±2.0 | 16.7±1.9 | 0.009‡ |
cpRNFL thickness (μm) (median[25,75 percentile]) | 98 (90, 106) | 57 (44, 63) | <0.001† |
MD (dB) (median[25,75 percentile]) | 0.1 (-0.3, 0.3) | -15.2 (-16.5, -12.9) | <0.001† |
Plus-minus values are means ± SD.
*Chi-square test,
†Mann–Whitney U test,
‡Unpaired t-test
Abbreviations: POAG, primary open angle glaucoma; yrs, years; IOP, intraocular pressure; cpRNFL, circumpapillary retinal nerve fiber layer; MD, mean deviation; dB, decibels; D, diopters