Table 2. Results of generalized linear mixed models for pulmonary obstruction with random intercept and slope for each patient.

	Univariable analysis		Multivariable analysis
	OR (95% CI)	p-value	OR (95% CI)	p-value
Age	1.23 (1.09–1.39)	0.0008	1.22 (1.08–1.39)	0.001
Male sex	86.80 (6.06–1242.78)	0.001	17.92 (1.28–251.64)	0.032
Smoking	51.80 (2.10–1277.70)	0.016	30.48 (1.58–586.72)	0.024
MSSI ‡	1.12 (1.00–1.25)	0.049	1.01 (0.92–1.10)	0.91
Residual α-GAL* activity	0.97 (0.93–1.01)	0.14
ERT †	451.18 (8.19–24956.63)	0.003	148.55 (0.80–27496.70)	0.06

* α-GAL, α-galactosidase A

^† ERT, enzyme replacement therapy

^‡ MSSI, Mainz Severity Score Index