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| Slope FEV1*, ml (CI) | p-value | |
|---|---|---|
| Male | -38 (-48, -27) | 0.009 |
| Female | -20 (-30, -11) | |
| Smoker | -33 (-47, -19) | |
| Non-smoker | -29 (-38, -20) | 0.60 |
| ERT† | -31 (-39, -24) | |
| ERT† naive | 23 (-32, -14) | 0.004 |
| MSSI‡, 0–20 points | -28 (-38, -17) | |
| MSSI‡, 20–40 points | -31 (-46, -15) | 0.33 |
| MSSI‡, 40–60 points | -41 (-73, -10) |
† ERT, enzyme replacement therapy
* FEV1, forced expiratory volume in first second
‡ MSSI, Mainz Severity Score Index
