Table 5.

Male and Female Fibrosis (percentage of LV Area)

Age	Sex	Exposure Duration	Control	BPA 2.5	BPA 25	BPA 250	BPA 2500	BPA 25000	EE2 0.05	EE2 0.5
PND 21	Male	-	0.94 ± 0.33 (10)	1.37 ± 0.37 (8)	1.33 ± 0.66 (8)	0.98 ± 0.42 (9)	1.12 ± 0.43 (10)	0.99 ± 0.26 (10)	1.13 ± 0.33 (10)	1.40 ± 0.55 (10)a
	Female	-	1.14 ± 0.55 (10)	1.09 ± 0.27 (10)	1.16 ± 0.43 (10)	1.11 ± 0.45 (10)	1.32 ± 0.42 (10)	1.16 ± 0.30 (10)	1.22 ± 0.49 (10)	1.02 ± 0.38 (10)
PND 90	Male	Stop	2.34 ± 0.86 (10)	2.32 ± 0.54 (9)	2.63 ± 0.81 (8)	3.04 ± 1.08 (10)	3.23 ± 1.05 (9)	2.90 ± 1.06 (10)	2.61 ± 0.60 (10)	2.81 ± 0.61 (9)
	Male	Continuous	3.38 ± 1.18 (10)	3.09 ± 0.96 (9)	3.44 ± 0.93 (8)	3.09 ± 1.19 (10)	4.18 ± 1.06 (8)	2.36 ± 0.39 (9)	3.41 ± 1.08 (10)	3.65 ± 1.10 (10)
	Female	Stop	2.70 ± 1.34 (10)	2.46 ± 0.88 (8)	2.64 ± 1.1 (10)	2.59 ± 0.72 (10)	3.16 ± 1.32 (8)	3.11 ± 1.02 (10)	2.01 ± 0.41 (10)	2.31 ± 0.57 (10)
	Female	Continuous	3.13 ± 0.90 (10)	2.74 ± 1.21 (10)	2.81 ± 0.82 (9)	3.13 ± 1.02 (10)	3.16 ± 0.97 (9)	2.14 ± 0.53 (9)b	2.88 ± 1.01 (10)	3.00 ± 1.13 (10)
6 Month	Male	Stop	2.50 ± 0.82 (10)	2.19 ± 0.89 (10)	1.88 ± 0.52 (9)	2.19 ± 0.88 (10)	2.47 ± 0.67 (9)	2.35 ± 0.75 (10)	2.60 ± 0.64 (10)	2.54 ± 0.99 (10)
	Male	Continuous	2.48 ± 0.77 (10)	2.29 ± 0.59 (9)	2.50 ± 1.00 (10)	2.45 0.93 (10)	2.69 ± 0.79 (8)	3.28 ± 1.40 (10)	2.18 ± 0.43 (9)	2.30 ± 0.42 (8)
	Female	Stop	2.82 ± 0.83 (10)	2.99 ± 1.10 (10)	2.88 ± 1.08 (10)	2.58 ± 1.14 (10)	2.31 ± 0.68 (10)	2.96 ± 0.68 (9)	2.23 ± 0.43 (9)	1.90 ± 0.60 (10)c
	Female	Continuous	2.31 ± 1.08 (10)	2.47 ± 0.96 (10)	2.35 ± 0.89 (10)	2.17 ± 0.43 (10)	2.83 ± 1.01 (10)	2.69 ± 0.90 (10)	2.59 ± 0.92 (10)	2.47 ± 1.02 (10)

Values represent group mean ± SD; the number of samples analyzed is shown in parenthesis.

^ap = 0.03, d = 1.15;

^bp=0.08, d = 1.46;

^cp =0.006 d = 1.37