Table 2.
Summary of Surveillance Round, Imaging Results, and Tumor Stage of Detected Cancers
| Patient No. | Age (years) | Mutation Status | Surveillance Round (No.) | BI-RADS Category |
Histology | TNM Stage |
Tumor Grade | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| US | MG | MRI | T | N | M | ||||||
| 1 | 45 | BRCA2 | 1 | 1 | 4 | 3 | IDC | mic | 0 | 0 | 3 |
| 2 | 34 | UV | 1 | 1 | 1 | 4 | DCIS | is | 0 | 0 | 2 |
| 3 | 55 | UV | 1 | 3 | 3 | 4 | DCIS | is | 0 | 0 | 2 |
| 4 | 38 | BRCA1 | 1 | 4 | 4 | 4 | DCIS | is | 0 | 0 | 2 |
| 5 | 55 | Unknown | 1 | 4 | 4 | 5 | DCIS | is | 0 | 0 | 1 |
| 6 | 55 | Unknown | 1 | 4 | 4 | 5 | DCIS | is | 0 | 0 | 1 |
| 7 | 52 | UV | 1 | 4 | 1 | 4 | DCIS | is | 0 | 0 | 3 |
| 8 | 31 | Unknown | 1 | 1 | 1 | 4 | DCIS | is | 0 | 0 | 2 |
| 9 | 48 | Wild type | 1 | 1 | 4 | 4 | DCIS | is | 0 | 0 | 1 |
| 10 | 35 | BRCA1 | 1 | 5 | 5 | 5 | IDC | 2 | 1b | 0 | 3 |
| 11 | 42 | BRCA1 | 1 | 1 | 1 | 4 | IDC | 1b | 0 | 0 | 3 |
| 12 | 62 | Unknown | 1 | 1 | 1 | 4 | IDC | 1b | 0 | 0 | 2 |
| 13 | 48 | UV | 1 | 1 | 1 | 5 | IDC | 2 | 0 | 0 | 3 |
| 14 | 41 | Unknown | 1 | 5 | 1 | 5 | IDC | 2 | 1a | 0 | 2 |
| 15 | 66 | Wild type | 1 | 5 | 1 | 5 | IDC | 1c | 0 | 0 | 2 |
| 16 | 43 | Unknown | 1 | 1 | 1 | 4 | IDC | 1b | 0 | 0 | 1 |
| 17 | 63 | Wild type | 1 | 5 | 5 | 4 | IDC | 1c | 0 | 0 | 2 |
| 18 | 53 | BRCA1 | 1 | 1 | 1 | 3 | IDC | 1a | 0 | 0 | 1 |
| 19 | 27 | Unknown | 1 | 5 | 5 | 5 | Metastasis from ovarian cancer | NA | NA | NA | NA |
| 20 | 49 | UV | 2 | 2 | 2 | 4 | DCIS | is | 0 | 0 | 1 |
| 21 | 41 | BRCA2 | 2 | 1 | 1 | 4 | IDC | mic | 0 | 0 | 3 |
| 22 | 53 | Wild type | 2 | 1 | 1 | 4 | DCIS | is | 0 | 0 | 2 |
| 23 | 50 | Wild type | 2 | 1 | 1 | 4 | DCIS | is | 0 | 0 | 3 |
| 24 | 46 | BRCA2 | 2 | 1 | 4 | 4 | DCIS | is | 0 | 0 | 2 |
| 25 | 36 | BRCA1 | 2 | 4 | 4 | 5 | IDC | 1b | 0 | 0 | 3 |
| 26 | 64 | UV | 2 | 2 | 1 | 4 | IDC | 1a | 0 | 0 | 1 |
| 27 | 36 | UV | 3 | 1 | 1 | 4 | IDC | mic | 0 | 0 | 3 |
| 28 | 42 | BRCA2 | 3 | 2 | 2 | 4 | DCIS | is | 0 | 0 | 2 |
| 29 | 43 | UV | 3 | 1 | 4 | 4 | IDC | mic | 0 | 0 | 3 |
| 30 | 42 | BRCA2 | 3 | 2 | 2 | 4 | IDC | 1a | 0 | 0 | 2 |
| 31 | 62 | UV | 3 | 4 | 4 | 4 | IDC | 1c | 0 | 0 | 3 |
| 32 | 47 | UV | 3 | 4 | 1 | 4 | IDC | 1c | 1a | 0 | 2 |
| 33 | 32 | BRCA1 | 3 | 1 | 1 | 4 | IDC | 1c | 0 | 0 | 2 |
| 34 | 62 | Wild type | 3 | 1 | 4 | 3 | Mucinous IDC recurrence | n/a | 0 | 0 | 2 |
| 35 | 41 | UV | 4 | 2 | 2 | 4 | IDC | 1b | 0 | 0 | 2 |
| 36 | 80 | BRCA2 | 4 | 5 | 5 | 4 | IDC | 1c | 0 | 0 | 3 |
| 37 | 43 | BRCA1 | 4 | 5 | 5 | 5 | Medullary carcinoma | 2 | 0 | 0 | 3 |
| 38 | 48 | BRCA1 | 5 | 2 | 2 | 4 | IDC | 1b | 0 | 0 | 3 |
| 39 | 55 | BRCA1 | 7 | 4 | 1 | 4 | DCIS | is | 0 | 0 | 3 |
| 40 | 38 | BRCA1 | 5 (interval) | 2 | 2 | 1 | Medullary carcinoma | 1c | 0 | 0 | 3 |
Abbreviations: BI-RADS, Breast Imaging and Reporting Data System; DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma; is, in situ; M, metastasis; MG, mammography; mic, microinvasion; MRI, magnetic resonance imaging; N, node status; NA, not applicable; T, tumor; US, ultrasound; UV, unclassified variant.