Scheme 2.
Reagents and conditions: (a) 3-indolyl acetaldehyde 8, AcOH, MeOH, Na(CN)BH3, 23 °C (24%); (b) 3-indolylacetic acid, EDC, HOBt, iPr2NEt, THF, 23 °C (75%); (c) LiAlH4, THF, 80 °C (74%).
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