Table 2.
Brain area | Control | Primary | Bystander | ANOVA |
---|---|---|---|---|
Anterior cingulate (CG1) | 156.6 ± 14.28 | 220.8 ± 28.66 | 251.9 ± 20.18* | F(2,14) = 4.77 |
Anterior cingulate (CG2) | 73.56 ± 5.65 | 75.14 ± 20.05 | 77.33 ± 14.12 | F(2,15) = 0.017 |
GranularInsula (GI) | 19.08 ± 2.752 | 23.89 ± 2.695 | 24.46 ± 6.201 | F(2,16) = 0.547 |
Agranular insula (INS) | 36.1 ± 3.73 | 50.86 ± 9.032 | 73.02 ± 15.59* | F(2,15) = 3.779 |
Somatosensory | 542.1 ± 44.79 | 659.8 ± 168.7 | 449.6 ± 76.52 | F(2,16) = 1.147 |
Dorsal lateral septum | 6.893 ± 1.542 | 6.958 ± 2.021 | 6.5 ± 1.351 | F(2,17) = 0.023 |
Intermediate lateral septum | 23.82 ± 2.326 | 23.71 ± 1.429 | 19.44 ± 2.637 | F(2,17) = 1.250 |
Ventral lateral septum | 13.65 ± 0.991 | 14.36 ± 3.342 | 12.27 ± 2.743 | F(2,17) = 0.183 |
Nucleus accumbens | 21.65 ± 6.323 | 25.76 ± 5.959 | 23.02 ± 3.265 | F(2,16) = 0.155 |
Bed nucleus of the stria terminalis (anterior) | 30.89 ± 2.2 | 48 ± 11.1 | 39.14 ± 5.47 | F(2,17) = 1.561 |
Bed nucleus of the stria terminalis (posterior) | 20.53 ± 8.444 | 25.45 ± 2.91 | 23.33 ± 4.889 | F(2,15) = 1.472 |
Dentate gyrus | 36.19 ± 5.337 | 39.14 ± 6.744 | 31.27 ± 6.609 | F(2,17) = 0.4011 |
Posterolateral cortical amygdaloid | 24.69 ± 2.328 | 17.3 ± 3.412 | 16.6 ± 1.027 | F(2,16) = 2.845 |
Posteromedial cortical amygdaloid | 9.571 ± 1.852 | 7.571 ± 1.242 | 8.722 ± 0.604 | F(2,17) = 0.5452 |
Basolateral amygdala | 12.61 ± 12.61 | 12.13 ± 2.592 | 17.78 ± 4.901 | F(2,15) = 0.7956 |
Central nucleus of the amygdala | 9.063 ± 1.194 | 5.833 ± 1.153 | 10.02 ± 2.409 | F(2,15) = 1.687 |
Paraventricular nucleus | 3.4 ± 0.75 | 11.17 ± 3.55 | 12.13 ± 3.29 | F(2,12) = 2.584 |
Dorsal medial hypothalamus | 16.15 ± 2.251 | 30.59 ± 5.143** | 20.73 ± 2.242 | F(2,16) = 4.842 |
Centrally projecting Edinger Westphal | 7.988 ± 1.276 | 12.16 ± 3.073 | 11.38 ± 1.799 | F(2,17) = 1.150 |
Periaqueductal gray | 44.98 ± 7.049 | 79.96 ± 19.14 | 63.9 ± 8.827 | F(2,17) = 2.073 |
Substantia nigra | 4.679 ± 2.298 | 7.917 ± 2.546 | 6.107 ± 1.603 | F(2,17) = 0.5495 |
Ventral tegmental area | 2.93 ± 1.02 | 4.88 ± 2.54 | 9.43 ± 4.66 | F(2,15) = 1.115 |
Mean (±SEM) c-Fos-positive cell counts for experimental each group per brain area examined. ANOVA values are presented in the right column, with significant main effects of group in bold. *p < 0.05 contrast to controls, Fishers LSD.