Table 3.
Multivariate analysis of risk factors associated with postoperative complications
| Characteristic | OR | 95%CI | P value |
| Age ≥ 75 yr | 1.053 | 0.248-4.470 | 0.945 |
| Sex | 0.572 | 0.237-1.380 | 0.214 |
| BMI of < 18.5 kg/m2 | 0.147 | 0.013-1.666 | 0.122 |
| Comorbidities | |||
| Diabetes mellitus | 1.234 | 0.322-4.726 | 0.759 |
| Hypertension | 0.989 | 0.397-2.463 | 0.981 |
| Preoperative serum albumin of < 35 g/L | 0.914 | 0.897-1.067 | 0.093 |
| Preoperative hemoglobin of < 120 g/L | 1.804 | 0.748-4.353 | 0.189 |
| Preoperative CRP of ≥ 10 g/L | 1.008 | 0.210-4.840 | 0.993 |
| CA 19-9 of ≥ 37 ng/mL | 1.197 | 0.431-3.327 | 0.730 |
| CEA of ≥ 5 ng/mL | 0.794 | 0.233-2.706 | 0.713 |
| Lymphocyte count of ≥ 3 × 109/L | 0.192 | 0.018-2.048 | 0.172 |
| CRP on POD 3 in mg/L | 4.296 | 1.887-9.780 | 0.001 |
| △ALB of ≥ 14.0% | 17.957 | 6.073-53.095 | < 0.001 |
| ASA of ≥ 3 | 0.929 | 0.406-2.127 | 0.861 |
| Clinical stage of ≥ II | 1.198 | 0.355-2.286 | 0.109 |
| Mode of surgical approach | 1.737 | 0.576-5.235 | 0.327 |
| Type of resection | 0.791 | 0.506-1.896 | 0.063 |
| Degree of lymph node dissection ≥ 2 | 3.485 | 1.163-10.446 | 0.026 |
| Operation time of ≥ 250 min | 1.448 | 0.624-3.355 | 0.389 |
| Blood loss of ≥ 200 mL | 1.418 | 0.636-3.160 | 0.393 |
∆ALB: (Albumin level before surgery-albumin on POD 1)/albumin level before surgery × 100%; ASA: American Society of Anesthesiologists; BMI: Body mass index; CA 19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; CRP: C-reactive protein; POD: Postoperative day.