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. 2017 Jul 26;9:238. doi: 10.3389/fnagi.2017.00238

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Copyright © 2017 Xiong, Lu, Zhu, Zeng, Shi, Jing, Xiang, Li, Tsang, Ruan and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MRI (3D-TOF) angiography showing morphological changes in diameter of vertebral arteries (VAs) in the vehicle and NBP-treated groups. Morphological changes in VAs are shown in the vehicle group (A) and NBP-treated group (B). Both CCAs were visible pre-occlusion but were not after BBCAO. However, the diameter of both VAs gradually increased until 4 weeks after BCCAO. VA diameter progressively increased after NBP treatment. (C,D) Quantitative analysis showing the changes of left (C) and right (D) VA diameter from 1 to 4 weeks in the NBP-treated group and the vehicle-treated group. **p < 0.01.