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. 2017 Jul 25;7:6358. doi: 10.1038/s41598-017-06723-w

Table 1.

Demographics, employment status, anthropometric, health behaviors, physical activity, sleep, social jetlag and metabolic variables according to obesity status (n = 792)

Variables All (n = 792) Non-obese (n = 369) MHO (n = 252) MUO (n = 171) p*
Age (years) 55.9 ± 12.4 55.6 ± 12.3 55.4 ± 13.4 56.4 ± 13.6 0.17
Female (%) 581 (73.0) 269 (73.1) 189 (75.3) 122 (71.3) 0.65
Marital status – Married (%) 401 (51.0) 188 (51.0) 131 (52.0) 82 (48.5) 0.42
Family income – (U$ 553.0) 504 (63.0) 235 (63.7) 151 (60.0) 118 (69.4) 0.36
Education – <= 12 years 507 (64.0) 231 (62.6) 165 (65.4) 123 (72.0) 0.37
Employment status
 Day workers (%) 333 (42.0) 144 (38.7) 96 (40.0) 68 (39.6) 0.88
 Retired (%) 256 (32.0) 132 (36.3) 91 (33.6) 57 (33.5)
 Hours per week 40.8 ± 8.9 41.0 ± 6.7 39.4 ± 7.9 42.4 ± 7.1 0.12
 Ex-night worker 37 (5.0) 22 (2.8) 7 (4.7) 8 (6.0) 0.17
Health behaviours
 Smoking status – Yes (%) 96 (12.0) 55 (15.0) 27 (10.7) 14 (8.1) 0.05
 Alcohol intake – Yes (%) 220 (28.0) 103 (28.0) 75 (29.7) 41 (24.0) 0.26
 Alcohol – Servings/week 2.0 [0.75–6.0] 2.0 [0.5–7.0] 2.0 [1.0–5.2] 2.3 [0.5–5.0] 0.86
 Physical activity (PA) – Yes (%) 294 (37.0) 134 (36.4) 93 (37.0) 67 (39.1) 0.82
 Minutes of PA/weekΧ 180 [120–300] 190 [120–300] 170 [120–300] 180 [120–290] 0.31
Chronic diseases
 Type 2 diabetes mellitus (TD2) (%) 257 (33.0) 111 (30.0) 57 (22.6) 89 (52.3) <0.001
 Arterial hypertension (SAH) (%) 526 (66.4) 223 (63.0) 174 (69.0) 129 (75.4) 0.02
 Dyslipidemia (%) 324 (41.0) 148 (40.0) 89 (35.4) 87 (50.8) <0.006
 Time of diagnosis of TD2λ 5.0 [3.0–10.0] 6.0 [3.0–10.0] 9.5 [4.0–16.0] 6.0 [3.0–10.0] 0.63
 Time of diagnosis of SAHλ 10 [5.0–15.0] 10.0 [5.0–15.0] 8.0 [2.0–15.0] 10.0 [5.0–18.0] 0.15
 Time of diagnosis of dyslipidaemiaλ 5.0 [2.0–10.0] 4.0 [2.0–8.0] 4.0 [2.0–10.0] 5.0 [3.0–10.0] 0.13
Anthropometric
 BMI (kg/m2) 30.0 ± 6.3 25.1 ± 0.2a 33.4 ± 0.2b 33.6 ± 0.3b <0.001
 Abdominal obesity (%)Ω 564 (71.0) 173 (47.0) 224 (89.0) 167 (98.0) <0.001
 High neck circumference (%)Φ 518 (65.0) 155 (42.2) 209 (83.2) 154 (90.0) <0.001
Food intake
 Kcal (kcal/day) 1467.5 [1212.3–1796.8] 1439.5 [1199.5–1764.8] 1496.4 [1221.5–1857.3] 1511.1[1254.0–1860.0] 0.34
 Carbohydrate (g/day) 174.1 [137.0–215.1] 170.0 [136.1–213.6] 181.2 [136.3–226.5] 174.1 [137.0–215.1] 0.21
 Protein intake (g/day) 73.9 [55.7–98.8] 73.1 [56.4–94.6] 77.0 [55.0–104.2] 75.4 [56.3–102.7] 0.58
 Fat intake (g/day) 51.0 [35.2–69.0] 51.0 [34.5–67.3] 52.4 [36.4–73.2] 51.0 [35.2–70.0] 0.74
 Kcal after 9 p.m. (kcal/day) 0 [0–165.4] 0 [0–204.8] 0 [0–138] 0 [0–130.0] 0.70
Circadian
 Chronotype – MSFsc (h)Ψ 02:54 [02:06–03:48] 02:48 [02:00–02:42] 02:59 [2:07–03:49] 02:55 [02:12–03:54] 0.72
 Morning (%) 633 (79.0) 296 (80.2) 197 (78.1) 139 (81.2) 0.83
 Intermediate (%) 77 (9.7) 33 (9.0) 29 (11.5) 15 (8.8)
 Late (%) 83 (10.4) 40 (10.8) 26 (10.3) 17 (10.0)
 Bedtime weekday (h)δ 22:20 [21:20–23:20] 22:20 [21:49–23:00] 22:22 [21:20–23:30] 22:24 [21:13–23:25] 0.93
 Bedtime weekend (h)δ 22:50 [21:50–24:00] 22:48 [21:37–23:00] 22:55 [21:52–23:55] 22:49 [21:50–23:51] 0.35
 Waketime weekday (h)δ 06:00 [05:30–07:00] 06:00 [05:30–07:00] 06:22 [06:00–07:00] 06:00 [05:30–07:30] 0.43
 Waketime weekend (h δ 07:00 [06:00–08:30] 07:00 [06:00–08:30] 07:00 [06:00–08:30] 07:00 [06:00–08:00] 0.48
 Sleep duration weekday (h) 07:30 [06:30–09:00] 07:30 [07:00–09:00] 07:30 [06:30–09:00] 07:00 [06:30–09:00] 0.32
 Sleep duration weekend (h) 08:00 [07:00–09:00] 08:00 [07:00–09:00] 08:00 [07:00–09:00] 08:00 [07:30–09:00] 0.36
 Mean sleeping duration (h) 07:29 ± 01:50 07:36 ± 01:47 07:25 ± 02:05 07:23 + 01:50 0.65
 Social jetlag (h) 00:30 [00:00–01:00] 00:30 [00:00–01:00] 0:30 [0:00–01:00] 0:25 [0:00–01:15] 0.97
 Social jetlag <= 1 h (%) 524 (66.0) 279 (75.6) 193 (76.6) 126 (73.6) 0.42
 Social jetlag >1 h and <2 h (%) 117 (14.0) 48 (13.0) 39 (15.4) 30 (17.4)
 Social jetlag >  = 2 h (%) 77 (10.0) 42 (11.3) 20 (8.0) 15 (9.0)

*One-way ANOVA and Tukey post hoc analyses were performed for normally distributed variables. When the variables were not normally distributed, Kruskal–Wallis tests were used. Variables with significant values in the Kruskal–Wallis test were tested by Dunn’s test with a correction of alpha via Bonferroni’s method. Values are presented as mean and SD for normally distributed data or as median (interquartile range) for non-normally distributed data. ΨChronotype (MSF) was derived from time of mid-sleep on free days (weekend), with further correction for calculated sleep debt – the difference between average sleep duration at weekends and on weekdays. δTime is presented in 24-h clock time. Diagnosis of hypercholesterolaemia, hypertriglyceridaemia or reduced HDL-C. ΩWaist circumference ≥ 102 cm for men and ≥ 88 cm for women were considered abdominal obesity. ΦNeck circumference ≥ 39 cm for men and ≥ 35 cm for women were considered high. λOnly those reported to have type 2 diabetes mellitus, systemic arterial hypertension or dyslipidaemia were included. ΧOnly those reported to perform physical activities. BMI: Body mass index. MHO: Metabolically healthy obese. MUO: Metabolically unhealthy obese.