Table 3.
Estimation of dN and dS substitution rate variation across the entire gene sequences of FUNDC1, MARCH5, BNIP3, and NIX in the lineages of teleost fishes, mammals and land vertebrates.
| Gene | Lineagea | dNb | dSb | ω (dN/dS)b |
|---|---|---|---|---|
| FUNDC1 | Teleost fishes | 0.055 | 1.191 | 0.040 |
| Mammals | 0.027 | 0.456 | 0.052 | |
| Land vertebrates | 0.066 | 1.011 | 0.060 | |
| MARCH5 | Teleost fishes | 1.224 | 0.019 | 0.016 |
| Mammals | 0.280 | 0.022 | 0.024 | |
| Land vertebrates | 0.694 | 0.019 | 0.020 | |
| BNIP3 | Teleost fishes | 0.137 | 1.341 | 0.095 |
| Mammals | 0.044 | 1.100 | 0.039 | |
| Land vertebrates | 0.080 | 1.598 | 0.041 | |
| NIX | Teleost fishes | 0.152 | 1.602 | 0.085 |
| Mammals | 0.054 | 0.710 | 0.049 | |
| Land vertebrates | 0.075 | 1.267 | 0.041 |
a
The relationship between teleost fishes and land vertebrates is displayed in Supplementary Figure 2.
b
dN means the number of synonymous substitutions per synonymous site and dS means the number of non-synonymous substitutions per non-synonymous site. dN and dS were estimated from the SNAP program (see Materials and Methods). ω estimates the relative rate of non-synonymous and synonymous substitutions (dN/dS). The ω value in teleost fishes was compared with those in mammals and land vertebrates, and the higher ω value is shown in bold.