Table 2.
The significant GO terms for the genes found to be differentially expressed between treatmentA (wt) and treatmentB (ko) their corresponding annotation for Biological Function (BF).
| GO.ID | Term | Annotated | Significant | Expected |
|---|---|---|---|---|
| GO:0015031 | protein transport | 1142 | 7 | 11.13 |
| GO:0051301 | cell division | 435 | 6 | 4.24 |
| GO:0006886 | intracellular protein transport | 653 | 5 | 6.36 |
| GO:0046777 | protein autophosphorylation | 170 | 0 | 1.66 |
| GO:0006915 | apoptotic process | 1336 | 29 | 13.02 |
| GO:0007067 | mitosis | 306 | 3 | 2.98 |
| GO:0006397 | mRNA processing | 322 | 2 | 3.14 |
| GO:0008285 | negative regulation of cell proliferation | 451 | 5 | 4.39 |
| GO:0001701 | in utero embryonic development | 374 | 3 | 3.64 |
| GO:0043065 | positive regulation of apoptotic process | 295 | 10 | 2.87 |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 534 | 5 | 5.2 |
| GO:0006281 | DNA repair | 357 | 0 | 3.48 |
| GO:0043066 | negative regulation of apoptotic process | 499 | 16 | 4.86 |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 715 | 12 | 6.97 |
| GO:0009968 | negative regulation of signal transduction | 692 | 10 | 6.74 |
| GO:0045893 | positive regulation of transcription, DNA-dependent | 991 | 15 | 9.66 |
| GO:0007049 | cell cycle | 1135 | 10 | 11.06 |
| GO:0001666 | response to hypoxia | 225 | 11 | 2.19 |
| GO:0006355 | regulation of transcription, DNA-dependent | 2844 | 31 | 27.71 |
| GO:0006468 | protein phosphorylation | 1156 | 17 | 11.26 |
Annotated: Number of genes associated to the GO term, Significant: Number of significantly differentially expressed (p <= 0.05) genes within the annotated genes, Expected: Number of genes within the annotated genes that are expected to be significantly deferentially expressed (p < = 0.05) by random.