Table 2.

Between- and within-group analysis of the proportion of patients with no, possible or probable anxiety and depression at each time point

	Pre-VR number (%)	6 months number (%)	12 months number (%)	Within-group analysis
				Pre-VR to 6 months p value	6 to 12 months p value	Pre-VR to 12 months p value
Control group
Anxiety
No case	21 (66)	23 (72)	24 (75)	0.73	1.00	0.38
Possible/probable	11 (34)	9 (28)	8 (25)
Depression
No case	20 (63)	25 (78)	24 (75)	0.18	1.00	0.22
Possible/probable	12 (37)	7 (22)	8 (25)
VR group
Anxiety
No case	23 (74)	28 (90)	29 (94)	0.06	1.00	0.03
Possible/probable	8 (26)	3 (10)	2 (6)
Depression
No case	25 (81)	29 (94)	29 (94)	0.29	1.00	0.22
Possible/probable	6 (19)	2 (6)	2 (6)
Between-group analysis
Anxiety	p = 0.50	p = 0.06	p = 0.04
Depression	p = 0.11	p = 0.08	p = 0.04

Statistical significance (p < 0.05) indicated by italic font

VR voice rehabilitation