Figure 3.

Zonal Analysis of Cellularity and Vascularization in iVT and Non-VT Hearts

(A) The relative proportion of MFB, FB, and vessels in zones 1 to 4 in iVT and non-VT hearts. The diameter of the circle is directly proportional to the cumulative number of cells per square millimeter. Because CM were analyzed using a different method (percentage of area coverage), these data are omitted here. Quantification of (B) CM, (C) blood vessels, (D) FB, and (E) MFB in zones 1 to 4 in iVT (black) and non-VT (gray) hearts. *p < 0.05. Data are from 5 and 4 iVT and non-VT hearts, respectively (4 to 7 sections for each zone per heart). All parameters in zones 1 to 3 are significantly different from normal myocardium (zone 4) in iVT and non-VT hearts, and from hearts from sham-operated control pigs (p < 0.05). Sham data are from 2 pigs (8 to 10 sections for each zone per pig). ND = not determined due to the absence of zone 2 in non-VT hearts; other abbreviations as in Figure 2.