Figure 5.

Late/LAVA Potentials Exhibit Cellular Profile Intermediate Between CI and BZ Regions

(A) Substrate map of late and/or LAVA sites (pink dots) located within the superior aspect of the border zone (BZ). (B) The corresponding surface electrocardiographic leads (I, II and III) in sinus rhythm and local bipolar electrograms at 3 of these LAVA sites (left, middle, right panels). Arrows indicate late and/or LAVA potentials. Analysis of the abundances of (C) CM, (D) blood vessels, (E) MFB, and (F) FB in late and/or LAVA potential sites compared with zones 2 (VT critical isthmus [CI]) and 3 (BZ regions with poor pace map) in iVT hearts (data from Figure 3B to 3E). Seventeen sections obtained from 3 iVT hearts (pigs 4, 11, and 16) were analyzed. The single incidence of late and/or LAVA potentials in a non-VT heart (pig 6) was not analyzed. *p < 0.05. Abbreviations as Figures 1 and 2.