Figure 1.
The replication of Legionella pneumophila inside the cell (Figure adapted from 23)
Wild-type and mutant form of Legionella use different ways for trafficking pathways(a) dot/icm mutants and trafficking pathway, (b) Wild-type of Legionella Pneumophila, the LCV formed and avoids endosomal fusion, (c) The Dot/Icm different effectors, (d) Host cell is prevented from death by the Dot/Icm effectors SdhA and Sid F, (e) the Dot/Icm effecter LubX effect the host cell factor Clk1, (f) the LCV was surrounded with Ribosomes, (g) Several cycle of Legionella Pneumophila replication,(h) Legionella Pneumophila Dot/Icm effectors LepA and B cause to Legionella pneumophila infect the other neighbour host cell Dot/Icm-translocated effectors is shown in green.23