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Knockdown of H19 inhibits UM1 xenograft lung metastasis in BALB/c-nu mice. UM1-sh-NC and UM1-sh19s cells were injected into nude mice (n=5/group). (A) Images of tumors from all mice in each group. Knockdown of H19 expression by lentivirus can remarkably attenuate the tumor growth and formation. (B) Mean tumor weight (left panel), tumor volume (right panel), and (C) lung metastasis stained by H&E were analyzed.
