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. Author manuscript; available in PMC: 2017 Jul 26.
Published in final edited form as: Cell Rep. 2017 Feb 28;18(9):2077–2087. doi: 10.1016/j.celrep.2017.02.004

Figure 2. BHB regulates neutrophil NLRP3 inflammasome activation.

Figure 2

IL-1β secretion by stimulated (A) mouse and (B) human neutrophils. (C) Secretion of S100A8 from stimulated human neutrophils. Different colored symbols connected by dotted line represents a unique individual’s response to all treatments. Columns indicate the mean for each treatment. (D, E) Western blot analysis of IL-1β secretion of adult and old murine neutrophils. (F) Depiction of insulin-induced hypoglycemia in vivo; arrow indicates blood collection time point. (G) Neutrophil IL-1β secretion from hypoglycemic subjects. Lines connect the responses of each individual for each treatment condition. Statistical differences were calculated by paired 1-way ANOVA. See also Figure S2.