TABLE 3.
Aries Flu A/B & RSV assay clinical performance summary in comparison to xTAG RVP assaya
| Virus | Sensitivity (PPA [%]) |
Specificity (NPA [%]) |
Positive predictive value (%) |
Negative predictive value (%) |
||||
|---|---|---|---|---|---|---|---|---|
| TP/(TP + FN) | 95% CI | TN/(TN + FP) | 95% CI | TP/(TP + FP) | 95% CI | TN/(TN + FN) | 95% CI | |
| Influenza Ab | 95.8 (299/312) | 93.0–97.8 | 98.4 (2,131/2,165) | 97.8–98.9 | 89.8 (299/333) | 86.0–92.8 | 99.4 (2,131/2,144) | 99.0–99.7 |
| Influenza B | 93.8 (45/48) | 82.8–98.7 | 99.4 (2,417/2,431) | 99.0–99.7 | 76.3 (45/59) | 63.4–86.4 | 99.9 (2,417/2,420) | 99.6–99.9 |
| RSV | 97.1 (270/278) | 94.4–98.7 | 98.4 (2,165/2,201) | 97.7–98.9 | 88.2 (270/306) | 84.1–91.6 | 99.6 (2,165/2,173) | 99.3–99.8 |
a
FN, false negative; FP, false positive; NPA, negative percent agreement; PPA, positive percent agreement; TN, true negative; TP, true positive.
b
Two specimens yielded invalid results for influenza A virus upon repeat xTAG RVP testing; both specimens were excluded from the assay performance calculations for this virus.