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. 2017 Mar 17;11(4):422–437. doi: 10.1002/1878-0261.12045

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© 2017 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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qRT‐PCR analysis of the expression of 21 genes selected from the RNA‐seq results. Control: normal SMMC‐7721 cell line; sh‐circ: knockdown treatment of circZKSCAN1 in the SMMC‐7721 cell line; over‐circ: overexpression treatment of circZKSCAN1 in the SMMC‐7721 cell line; sh‐linear: knockdown treatment of ZKSCAN1 in the SMMC‐7721 cell line; over‐linear: overexpression treatment of ZKSCAN1 in the SMMC‐7721 cell line. The y‐axis shows the gene expression levels after normalization to the reference gene GAPDH. *P <0.05, compared with NC.