Fig. 2. IU1 treatment improves survival and functional recovery following I/R.
A. Body weight of IU1- and vehicle-treated mice. Mice were treated either with IU1 (400 μg/kg) or vehicle 2 h after 1 h-MCAO. Mice were then allowed to survive for 7 days and received the same dose of daily treatment after the surgery. Data are shown as Mean ± SEM; n = 7 – 8 for each group of mice.
B. IU1-treated mice show improved survival rate compared to the vehicle-treated mice. n = 7 – 8 in each group.
C. IU1-treated mice show more rapid functional recovery than the vehicle-treated mice. Data are shown as median value ± SEM; n = 7–8; *p < 0.05 (Tukey’s test).