Table 1.

Modified neurologic severity scores (mNSS) (Chen et al. 2005)

Behavioral Tests	Sore points
Raising the mouse by the tail
• Flexion of forelimb	1
• Flexion of hindlimb	1
• Head moved more than 10° to the vertical axis within 30 seconds	1
Walking on the floor (normal = 0; deficits = 1–3)
• Normal walk	0
• Inability to walk straight	1
• Circling toward the paretic side	2
• Falling down to the paretic side	3
Beam balance tests (normal = 0; deficits = 1–6)
• Balances with steady posture	0
• Grasps side of beam	1
• Hugs the beam and one limb falls down from the beam	2
• Hugs the beam and two limbs fall down from the beam, or spins on beam for more than 30 seconds	3
• Attempts to balance on the beam but falls off >20 seconds	4
• Attempts to balance on the beam but falls off >10 seconds	5
• Falls off: No attempt to balance or hang on to the beam >10 seconds	6
Reflexes absence (normal = 0; deficits =1–2)
• Absence of pinna reflex (normal, head shake upon touching the auditory meatus)	1
• Absence of corneal reflex (normal, an eye blink upon gently touching the cornea with cotton)	1
Maximum score points	14