TABLE 3.
Hazard ratios (95% confidence intervals) for predictors of living donor transplant, death or removal from the waiting list due to deteriorating condition, and removal for other reasons
| Reasons for removal from the waiting list | |||
|---|---|---|---|
|
|
|||
| Predictor | Living donor transplant | Death or deteriorating condition | Other |
| CPRA | 0.99 (0.99-0.99) | — | — |
| Age at listing | 0.98 (0.98-0.98) | 1.04 (1.04-1.04) | 1.00 (1.00-1.00) |
| Spline: age > 65 y | — | — | 1.10 (1.09–1.11) |
| Dialysis duration at listing | — | 1.18 (1.17–1.19) | — |
| Spline: dialysis time > 5 y | — | 0.83 (0.82–0.85) | — |
| Male | — | 1.06 (1.03–1.09) | 1.04 (1.00–1.08) |
| Diabetes | 0.54 (0.52–0.56) | 1.69 (1.64–1.73) | — |
| Angina/CAD | — | 1.33 (1.23–1.44) | — |
| Symptomatic CVD | — | 1.21 (1.14–1.29) | — |
| Drug-treated COPD | — | 1.58 (1.45–1.73) | — |
| Drug-treated systemic HTN | — | 0.91 (0.88–0.93) | — |
| Any previous malignancy | — | 1.11 (1.05–1.17) | — |
| Symptomatic PVD | — | 1.38 (1.32–1.45) | — |
| BMI | — | 0.95 (0.94–0.95) | — |
| Spline: BMI > 25 kg/m2 | — | 1.05 (1.04–1.06) | — |
| DSA SE | 0.41 | — | 0.53 |
| Concordance (SE) | 0.66 (0.004) | 0.67 (0.003) | 0.64 (0.005) |
All models include DSA as a random effect. Models for living donor transplant and removal from the list due to other reasons are stratified by recipient blood type. All candidate covariates are shown. Spline hazard ratios account for the different effect noted when age is > 65 years, dialysis time is > 5 years, and BMI is greater than 25 kg/m2. DSA is included in the model as a random effect, and the SE demonstrates the heterogeneity in time-to-event between DSAs.
CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CVD, cerebrovascular disease; HTN, hypertension; PVD, peripheral vascular disease.