FIG 1.

Linearized map of pS30-1 compared to other regions containing the tet39 resistance determinant module. Partial sequences are marked with an asterisk. Arrows indicate the extents and directions of genes and ORFs. The tetA gene and the tetR genes of tet39 are shown in red, and rep genes are shown in dark blue. Genes encoding putative toxin/antitoxin modules are shown in solid or patterned pink. The msrE and mphE resistance genes are shown in orange, tonB is dark gray, abi genes are light blue, and ser, encoding a serine recombinase, is shown in purple. Genes encoding proteins showing homology to mobilization proteins are shown in yellow. The tonB gene encodes a TonB-dependent transporter homologue. The light green box represents ISAjo2-1, and the arrow inside represents the transposase gene. The extents of regions with significant DNA identities are shown in gray, and the numbers represent DNA identities. Vertical bars indicate pdif sites; the orientation of each site is shown above, and flags indicate target site duplications. The picture is drawn to scale according to the GenBank entries listed in Table 1. The sequences of the pdif sites that flank the tet39 module are shown in the table at the bottom of the figure. The bases highlighted in red are different.