FIG 1.

Alignment of MexZ of Pseudomonas aeruginosa (PAO1 strain) and AxyZ of Achromobacter insuavis (AXX-A strain) (Clustal Omega). The area boxed with the solid line delimits the DNA-binding domain, and the area boxed with the dashed line delimits the C-terminal domain (41). Amino acid sequence similarity was as follows: overall, 59%; DNA-binding domain, 76%; C-terminal domain, 51%. Stars indicate identical residue positions; arrows indicate positions of substitutions detected in laboratory mutants, i.e., valine at position 29 and arginine at position 105.