Concentration-time data for penicillin G stability in DBS at initial concentrations of 1 and 30 mg/liter, stored at 35°C (○), 22°C (△), 4°C (□), and −20°C (●). Data are means ± standard deviations (SD). A monoexponential (first-order) equation was fitted to the data at 4°C and −20°C, and a biexponential equation was fitted to the data at 35°C and 21°C.