TABLE 1.
Clinical and epidemiological characteristics of 63 community hospital patients with multidrug-resistant E. coli infections
| Categorya | Specific variableb | No. of isolates (column %) |
|||||
|---|---|---|---|---|---|---|---|
| Total (n = 63) | ST131 (n = 39) | Non-ST131 (n = 24) | ST131 H30Rx (n = 27) | ST131 non-H30Rx (n = 12) | All non-H30Rx (n = 36) | ||
| Age >65 | 38 (60) | 24 (62) | 14 (58) | 16 (59) | 8 (67) | 22 (61) | |
| Sex | Male | 30 (48) | 19 (49) | 11 (46) | 14 (52) | 5 (42) | 16 (44) |
| Female | 26 (41) | 18 (46) | 8 (33) | 11 (41) | 7 (58) | 15 (42) | |
| Unknown | 7 (11) | 2 (5) | 5 (21) | 2 (7) | 0 | 5 (14) | |
| Race | African American | 19 (30) | 12 (31) | 7 (29) | 8 (30) | 4 (33) | 11 (31) |
| American Indian | 1 (2) | 0 | 1 (4) | 0 | 0 | 1 (3) | |
| Asian | 1 (2) | 0 | 1 (4) | 0 | 0 | 1 (3) | |
| Caucasian | 33 (52) | 23 (59) | 10 (42) | 15 (56) | 8 (67) | 18 (50) | |
| Hispanic | 1 (2) | 1 (3) | 0 | 1 (4) | 0 | 0 | |
| Unknown | 8 (13) | 3 (8) | 5 (21) | 3 (11) | 0 | 5 (14) | |
| Community hospital | A | 35 (56) | 21 (54) | 14 (58) | 16 (59) | 5 (42) | 19 (53) |
| B | 6 (10) | 4 (10) | 2 (8) | 3 (11) | 1 (8) | 3 (8) | |
| C | 10 (16) | 6 (15) | 4 (17) | 6 (22) | 0 | 4 (11) | |
| D | 8 (13) | 7 (18) | 1 (4) | 1 (4) | 6 (50) | 7 (19) | |
| E | 1 (2) | 1 (3) | 0 | 1 (4) | 0 | 0 | |
| F | 1 (2) | 0 | 1 (4) | 0 | 0 | 1 (3) | |
| G | 2 (3) | 0 | 2 (8) | 0 | 0 | 2 (6) | |
| Admission source | Home | 37 (59) | 21 (54) | 16 (67) | 12 (44) | 9 (75) | 25 (69) |
| Nursing home | 13 (21) | 10 (26) | 3 (13) | 8 (30) | 2 (17) | 5 (14) | |
| Transfer from hospital | 4 (6) | 3 (8) | 1 (4) | 2 (7) | 1 (8) | 2 (6) | |
| Other extended-care facility | 3 (5) | 3 (8) | 1 (4) | 3 (11) | 0 | 1 (3) | |
| Unknown | 5 (8) | 2 (5) | 3 (13) | 2 (7) | 0 | 3 (8) | |
| Type of infection | Urinary tract infection | 29 (46) | 19 (49) | 10 (42) | 13 (48) | 6 (50) | 16 (44) |
| Bloodstream infection | 21 (33) | 14 (36) | 7 (29) | 9 (33) | 5 (42) | 12 (33) | |
| Pneumonia | 1 (2) | 0 | 1 (4) | 0 | 0 | 1 (3) | |
| Other | 7 (11) | 4 (10) | 3 (13) | 3 (11) | 1 (8) | 4 (11) | |
| Unknown | 5 (8) | 2 (5) | 3 (13) | 2 (7) | 0 | 3 (8) | |
| Acquisition | Community acquired | 22 (35) | 14 (36) | 8 (33) | 8 (30) | 6 (50) | 14 (39) |
| Community onset, health care associated | 30 (48) | 20 (51) | 10 (42) | 15 (56) | 5 (42) | 15 (42) | |
| Hospital onset, health care associated | 6 (10) | 3 (8) | 3 (13) | 2 (7) | 1 (8) | 4 (11) | |
| Unknown | 5 (8) | 2 (5) | 3 (13) | 2 (7) | 0 | 3 (8) | |
| ICU stay | Before infection | 4 (6) | 2 (5) | 2 (8) | 1 (4) | 1 (8) | 3 (8) |
| After infection | 46 (73) | 30 (77) | 16 (67) | 20 (74) | 10 (83) | 26 (72) | |
| Unknown | 13 (21) | 7 (18) | 6 (25) | 6 (22) | 1 (8) | 7 (19) | |
| Dialysis | Yes | 4 (6) | 3 (8) | 1 (4) | 3 (11) | 0 | 1 (3) |
| No | 51 (81) | 32 (82) | 19 (79) | 20 (74) | 12 (100) | 31 (86) | |
| Unknown | 8 (13) | 4 (10) | 4 (17) | 4 (15) | 0 | 4 (11) | |
| Outcome | Died | 5 (8) | 4 (10) | 1 (4) | 3 (11) | 1 (8) | 2 (6) |
| Survived | 49 (78) | 30 (77) | 19 (79) | 20 (74) | 10 (83) | 29 (81) | |
| Discharged home | 22 (35) | 15 (38) | 7 (29) | 9 (33) | 6 (50) | 13 (36) | |
| Discharged to hospice | 5 (8) | 2 (5) | 3 (13) | 2 (7) | 0 | 3 (8) | |
| Discharged to LTCF | 16 (25) | 11 (28) | 5 (21) | 8 (30) | 3 (25) | 8 (22) | |
| Discharged to other facility | 6 (10) | 2 (5) | 4 (17) | 1 (4) | 1 (8) | 5 (14) | |
| Unknown | 9 (14) | 5 (13) | 4 (17) | 4 (15) | 1 (8) | 5 (14) | |
a
Category of clinical or epidemiological characteristic.
b
LTCF, long-term-care facility. All comparisons (ST131 versus non-ST131, H30Rx versus non-H30Rx ST131, or H30Rx versus non-H30Rx) yielded P values of >0.05, except for community hospital category D (for H30Rx versus non-H30Rx ST131, P = 0.002).