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ClfA-alpha-toxin bispecific antibodies compared to IgG1. (A) Bispecific constructs using anti-ClfA MAb as a scaffold. scFv of anti-alpha-toxin MAb MEDI4893* were linked via a 10-amino-acid linker (GGGGx2) to the ClfA MAb heavy-chain N terminus (B) or heavy-chain C terminus (C).
