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Mutation profile of linezolid-resistant M. tuberculosis. We show mutations present in nine linezolid-resistant M. tuberculosis isogenic strains compared to the wild type. A number of mutations, compared to wild type, occurred in genes encoding efflux pump/transporters (Rv0545c, Rv0930, Rv2477, and Rv3331), as well as in the luxR family transcriptional regulator Rv0890c.
