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Sterilizing activity of metformin in combination with the first-line regimen against chronic TB in mice
| Regimen | Percentage (proportion) relapse, assessed 12 wk after the completion of treatment for: |
||
|---|---|---|---|
| 3.5 mo | 4.5 mo | 5.5 mo | |
| 2 mo RHZE and 4 mo RH | 53.3 (8/15) | 20 (3/15) | 6.6 (1/15) |
| 2 mo RHZE and 4 mo RH + MetF | 46.6 (5/15) | 20 (3/15) | 0 (0/15) |
