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. 2017 Jul 25;61(8):e02602-16. doi: 10.1128/AAC.02602-16

FIG 3.

FIG 3

The overall structure of TMB-1. (A) The secondary structure of TMB-1 with active-site residues, including residue E119 (cyan), and the L1 (residues 60 to 66) and L3 (residues 223 to 240) loops (indicated in blue). (B) The TMB-1 active site, with the three zinc ions indicated in gray, the bridging water molecule indicated in red, and the two chlorine ions indicated in magenta. The residues binding Zn1 (H116, H118, and H196) and Zn2 (D120, C221, and H263) and residues V67, W64, W87, E119, R224, S228, and Y233 are described further in the paper.