TABLE 3.
ED50s of different anti-Toxoplasma drugs in vivo
| Compound | ED50 (range) in mice (mg/kg/day)a |
|---|---|
| C7S | 0.87 (0.77–0.89) |
| Risedronate | 0.22 (0.12–0.68) |
| Atorvastatin | 32.4 (14.1–70.4) |
| Zoledronate | 0.25 (0.17–0.51) |
| Atovaquone | 2.53 (1.82–4.17) |
a
The drugs were administered i.p. to groups of 5 mice during 10 days, and the results are expressed as the ED50 values calculated from the results of all experiments combined; the ranges of ED50s are calculated from the results of each of the three to four independent experiments using each drug.