TABLE 1.
Susceptibilities of the studied strains to β-lactams, by microdilution method
| Strain | Carbapenemase-encoding genes | MIC (μg/ml) ofa: |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| AMX | FOX | CAZ | CTX | FEP | IPM | ETP | MEM | ||
| WI1 | blaKPC-3 | >256 | 16 | >256 | >32 | 12 | 4 | 6 | 2 |
| WI2 | blaKPC-28, blaOXA-48 | >256 | 8 | >256 | 8 | 6 | 1 | 3 | 0.38 |
| E. coli DH5α-KPC-3 | blaKPC-3 | >256 | 8 | 4 | 1 | 1 | 1 | 0.125 | 0.25 |
| E. coli DH5α KPC-28 | blaKPC-28 | 64 | 8 | 64 | 0,5 | 1 | 0.125 | 0.032 | 0.032 |
| E. coli DH5α | 1 | 4 | 0.06 | 0.06 | 0.032 | 0.05 | 0.006 | 0.006 | |
a
AMX, amoxicillin; FOX, cefoxitin; CAZ, ceftazidime; CTX, cefotaxime; FEP, cefepime; IPM, imipenem; ETP, ertapenem; MEM, meropenem.