TABLE 2.
Clinical features of patients infected or colonized with OXA-232 carbapenemase-producing K. pneumoniae isolates
Patient no. | Age | Sex | Underlying condition | Days of hospital stay before infection/total days | Specimen | Invasive procedurea | Prior antibiotic exposure | Antimicrobial therapy | Infection or colonization | Status at hospital discharge |
---|---|---|---|---|---|---|---|---|---|---|
1 | 4 mo | Male | Neonatal pulmonary hypoplasia, neonatal pneumonia, septicemia | 1/180 | Sputum | Endotracheal intubation | SAM, MEM, VRO, CRO, IPM | SAM, MEM, FOS, SCF, VRO, CAZ, AMK, CIP | Infection | Died |
2 | 35 d | Male | Congenital laryngeal cartilage dysplasia, malrotation | 26/46 | Sputum | Endotracheal intubation, PICC | CDZ, CPC, SAM, MEM | FOS, MEM, SCF | Infection | Recovered |
3 | 4 d | Male | Neonatal respiratory distress syndrome, persistent pulmonary hypertension of newborn, congenital heart disease | 4/14 | Sputum | Endotracheal intubation | SAM, CTX | SAM, MEM | Infection | Recovered |
4 | 16 d | Male | Hyperbilirubinemia, hemolytic disease of newborn | 14/23 | Urine | None | SAM | SAM | Colonization | Recovered |
5 | 4 mo | Male | Neonatal pulmonary hypoplasia, anemia, neonatal abdominal distension | 98/114 | Urine | UVC, endotracheal intubation, intestinal surgery | SAM, CPC | MEM, FOS | Infection | Recovered |
PICC, peripherally inserted central catheter; UVC, umbilical venous catheter; AMK, amikacin; CDZ, cefodizime; CPC, cefepime; CIP, ciprofloxacin; CTX, cefotaxime; CAZ, ceftazidime; SAM, ampicillin-sulbactam; MEM, meropenem; IPM, imipenem; VRO, vancomycin; CRO, ceftriaxone; FOS, fosfomycin; SCF, cefoperazone-sulbactam.