TABLE 4.
Susceptibility of S. aureus strains to antibiotics and chemical compounds
| S. aureus strain | MIC (μg/ml) fora: |
||||||
|---|---|---|---|---|---|---|---|
| NOR | TET | CHL | ERY | Rh | CHG | TPP-Cl | |
| RN6390 | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT7 (Δtet38) | 0.5 | 0.03 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT21 (ΔtetR21) | 1.0 | 0.25 | 8 | 0.12 | 16 | 0.12 | 1.0 |
| QT18 (ΔlmrS) | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT1821 (ΔlmrS-ΔtetR21) | 1.0 | 0.25 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| RN6390 (pSK950)b | 0.5 | 4 | 0.06 | 8 | 0.06 | 0.5 | |
| RN6390 (pSK950-lmrS) | 0.5 | 16 | 0.12 | 16 | 0.12 | 2.0 | |
| RN6390 (pSK950-sdrM) | 0.5 | 4 | 0.06 | 8 | 0.06 | 0.5 | |
| RN6390 (pLZ113) | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT21 (pLZ113-tetR21) | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT18 (pLZ113-lmrS) | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
| QT1821 (pLZ113-tetR21, pLZ113-lmrS) | 0.5 | 0.06 | 4 | 0.06 | 8 | 0.06 | 0.5 |
a
NOR, norfloxacin; TET, tetracycline; CHL, chloramphenicol; ERY, erythromycin; Rh, rhodamine 6G; CHG, chlorhexidine; TPP-Cl, tetraphenylphosphonium chloride.
b
All strains harboring plasmid pSK950 were grown in the presence of tetracycline, 5 μg/ml, and at 30°C.