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Mutations in Rv0191, Rv3756c, Rv3008, and Rv1667c in PZA-resistant strains in the GMTV database
| Gene | No. of SNPsa | Most common nucleotide variation (no.) | Codon no. | Effectb |
|---|---|---|---|---|
| Rv0191 | 406 | GCT/ACT (299) | 213 | Nonsynon |
| GCC/GCT (87) | 66 | Synon | ||
| Rv3756c | 58 | GTT/GTG (42) | 78 | Synon |
| Rv3008 | 16c | |||
| Rv1667c | 19 | CCG/CCT (9) | 136 | Syn |
SNPs, single nucleotide polymorphisms.
Nonsyn, nonsynonymous; Syn, synonymous.
All 16 SNPs are distinct.
