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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Am Coll Surg. 2017 May 15;225(1):138–147. doi: 10.1016/j.jamcollsurg.2017.02.018

Figure 4.

Figure 4

Stratification of patients by internal normalized ratio (INR) increases predictability of identifying patients that require a massive transfusion using the high dose (Ht) tissue plasminogen activator (tPA) thrombelastography (TEG) time to maximum amplitude (TMA). Roughly half of patients in the study had an INR greater than 1.1. After stratification of these patients the Ht-TMA cut off of less than 16 minutes had a positive predictive value (PPV) of 49% while an INR of less than 1.1 had an overall negative predictive value of 98%. In this schematic, 14 patients were excluded due to the patient not having laboratory assessment of INR or Ht-TEG. MT, massive transfusion.