. 2008 May 28;2(2):153–160. doi: 10.1016/j.molonc.2008.05.003

Table 1.

Examples of proteomic technologies used for personalizing cancer therapy

Technologies	Applications
Glycoproteomics: the biochemical signature of cancer on cell membrane in the form of glycoproteins	Targeted cancer therapy against molecular targets expressed in tumors
Proteomic approaches plus biochemical assays to identify the target antigen	Antibody‐based therapies for cancer
Mass spectrometry‐based fingerprints of peptides/proteins plus laser capture microdissection and high density protein arrays	Proteomic profiling/molecular classification of human tumors
Determination of structure of protein kinases: important drug targets in cancer	Screening for personalized anticancer drugs
Reverse phase protein microarrays provide a functional map of known cell‐signaling networks or pathways (Espina et al., 2008)	Correlation of pathways with biological and clinical information for an individual patient obtained directly from a cancer biopsy specimen for personalization of therapy