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Expression of p53 and p53 target genes. (A) Western blot analysis of p53 in doxycycline‐treated H1299‐His175 and Saos‐2‐His273 cells. (B–D) Western blot analysis of the expression of p21 (B) and PUMA (C), and analysis of Bax expression (D) by immunofluorescence staining in STIMA‐1‐treated H1299 and H1299‐His175 cells. (C) PUMA protein expression is also induced by treatment with CP‐31398.
