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. 2008 Dec 11;3(1):24–32. doi: 10.1016/j.molonc.2008.12.002

Figure 1.

Figure 1

Schematic representing the role of measurements made during drug development. For ultimate drug approval risk/benefit is assessed by regulatory authorities. Prior to that, and providing a drug is judged safe, efficacy estimates are made to in an attempt to guide internal decisions and prioritise finite resources to the most promising candidates.