Fig. 3.

Summary of measurements of combed molecules. (A) Measurements from all combed molecules are shown, one molecule per line, in the order of total replication (left plus right). The length by which one replisome has outpaced the other is shown in red. Molecules in which this difference is statistically significant are indicated by *. (B) The offset (right minus left) measured in each combed molecule is plotted in the order of offset magnitude. Offsets between –14 and +2 kb are most common. Twenty-four molecules showed a leftward offset >6.8 kb, and eight molecules showed a rightward bias >6.8 kb.