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. 2008 Nov 5;3(1):77–83. doi: 10.1016/j.molonc.2008.10.004

Figure 5.

Figure 5

Ebselen positively affects the DNA mismatch repair system in TNFα treated cells. Ability of glioma cells to repair DNA mismatch both in the presence and absence of TNFα was detected by determining the expression of MSH2 and MLH1. Protein was isolated from A172 glioma cells treated with 10μM Ebselen in the presence or absence of TNFα and Western blot analysis was performed to detect the expression of MSH2 and MLH1. A representative blot is shown from three independent experiments with identical results. Blots were reprobed for β‐actin to establish equivalent loading.