Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
DNA methylation in normal and cancer cell. In a normal cell CpG islands (C) in actively transcribed promoter regions are not methylated allowing transcriptional activity (green arrow). CpG islands elsewhere, within genes and intergenic spaces are more often methylated (M). In a cancer cell the reverse is observed. Red line with X: repressed transcription.
