Skip to main content
. 2009 Nov 25;4(1):52–64. doi: 10.1016/j.molonc.2009.11.002

Figure 2.

Figure 2

Principal component analysis (PCA) and bridge partial least square analysis (PLS) on different rectal cancer patient samples. (A) Two‐dimensional PCA of differentially expressed genes (p<0.05), derived from 20 patients with rectal cancer, before and after radio‐chemotherapy (RCT), showing separation of the different sample groups. (B) The plot depicts the scores of the PLS model. Components 1 and 2 (left) look similar to PCA analysis shown in (A), but component 3 (right) clearly separates the sample groups for normal rectal tissue. All samples are colour coded according to group. Black: NN (normal rectal tissue); green: NR (irradiated normal rectal tissue samples); blue: TN (rectal tumour tissue samples); red: TR (irradiated rectal tumour samples). *Potential non‐responders.