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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Prostate. 2017 Jun 20;77(11):1187–1198. doi: 10.1002/pros.23377

Tab 2.

The ΔTm50 (°C) values are summarized for individual proteins from cell lysate (in vitro) and whole cell (in vivo) CETSA assays.

The ΔTm50 (C) values for individual proteins in vitro and in vivo

Compound cell lysate (in vitro)
whole cell (in vivo)
p110α p110β p110γ VPS34 Akt p110β Akt
TGX221 1.57 04.02 0.68 0.42 1.49 1.72 1.18
BL139 1.51 12.40 0.84 0.14 2.44 5.78 2.60
BL140 1.16 06.58 1.73 0.55 2.14 7.93 3.14
BL141 1.61 10.53 0.61 0.84 0.52 1.32 2.31
BL147 1.47 03.83 1.43 4.16 1.45 2.18 2.85