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. Author manuscript; available in PMC: 2017 Jul 26.

Published in final edited form as: J Biomed Mater Res A. 2014 Nov 18;103(7):2300–2308. doi: 10.1002/jbm.a.35366

Normal probability plot of the effects of the factors and their interactions. Effect of single factors is represented by A, B, C, D, E; their interactions with other variables are represented as AB, BC, etc. In this figure, A- Cys; B- pH; D- EDC; BD- two factorial interaction of pH and EDC. represents positive effects; while represents negative effects. The model is framed based on selecting the dominant factors that are highlighted and labeled in plots; other factors are considered as errors.

Inline graphic — Normal probability plot of the effects of the factors and their interactions. Effect of single factors is represented by A, B, C, D, E; their interactions with other variables are represented as AB, BC, etc. In this figure, A- Cys; B- pH; D- EDC; BD- two factorial interaction of pH and EDC. represents positive effects; while represents negative effects. The model is framed based on selecting the dominant factors that are highlighted and labeled in plots; other factors are considered as errors.