Table 3.

Hazard ratios for the Associations of Lifetime Discrimination and All-cause Mortality, Incident Stroke, Incident Coronary Heart Disease, and Heart Failure Hospitalization

Model	All-cause mortality		Incident stroke		Coronary heart disease		Heart failure hospitalization
	Hazard Ratio (95% CI) d	P-value	Hazard Ratio (95% CI) d	P-value	Hazard Ratio (95% CI) d	P-value	Hazard Ratio (95% CI) d	P-value
M1: Unadjusted	0.88 (0.85, 0.92)	< .001	0.88 (0.81, 0.95)	.001	0.91 (0.85, 0.97)	.007	0.91 (0.86, 0.96)	< .001
M2: Age and Sex	0.94 (0.90, 0.98)	.004	0.93 (0.86, 1.00)	.06	0.95 (0.89, 1.02)	.17	0.97 (0.92, 1.02)	.28
M3: M2+Behavioral/Clinicala	0.94 (0.91, 0.98)	.006	0.93 (0.86, 1.01)	.07	0.96 (0.89, 1.03)	.24	0.97 (0.92, 1.03)	.33
M4: M3+Socioeconomicb	0.96 (0.92, 1.00)	.04	0.94 (0.86, 1.02)	.12	0.96 (0.89, 1.03)	.27	0.99 (0.93, 1.04)	.65
M5: M4+Social Supportc	0.96 (0.92, 1.00)	.06	0.94 (0.86, 1.02)	.12	0.96 (0.89, 1.03)	.28	0.99 (0.94, 1.04)	.68

^aAdjusted for all variables in model 2 plus smoking status, BMI, hypertension, hypercholesterolemia, diabetes mellitus, estimated glomerular filtration rate

^bAdjusted for all variables in model 3 plus income, education, occupation, perceived standing in the community, healthcare access. Due to low event counts, 3 variables were re-parameterized to reduce the total degrees of freedom for the incident stroke and incident coronary heart disease models only: (1) income was reduced to 3 categories, (2) education was treated as continuous, and (3) occupation was dichotomized.

^cAdjusted for all variables in model 4 plus social support.

^dHazard ratios are per 1-point increase in lifetime discrimination