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. Author manuscript; available in PMC: 2017 Jul 26.
Published in final edited form as: Cell Rep. 2017 Apr 25;19(4):733–745. doi: 10.1016/j.celrep.2017.03.080

Figure 2. Increased colitis susceptibility in IL10−/−Nlrp6−/− mice does not transfer to IL10−/− mice upon cohousing.

Figure 2

(A) Representative micrographs and histological scoring of 12 week old IL10−/− (n=6) and IL10−/−Nlrp6−/− (n=8) mice after 2 months of cohousing. Arrows point to Inflammation and hyperplasia. Original magnification = 200x. (B) Spleen weights and (C) fecal lipocalin-2 levels from cohoused IL10−/− and IL10−/−Nlrp6−/− mice. (D) Relative mRNA expression of pro-inflammatory mediators in the colon of cohoused (COH) or non-cohoused IL10−/− and IL10−/−Nlrp6−/− mice (n=8). Data are representative of two independent experiments. * - p<0.05 as compared to IL10−/− mice. See also Figure S2.