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. Author manuscript; available in PMC: 2017 Jul 26.
Published in final edited form as: Mol Pharm. 2014 Apr 29;11(8):2539–2552. doi: 10.1021/mp500099g

Table 3.

miRNAs Regulate EMT in Prostate Cancers

miRNAa functions refs
miR-143 enhance E-cadherin;
reduce fibronectin		 97
miR-145 enhance E-cadherin;
reduce fibronectin; inhibit HEF1		 97,98
miR-29b enhance E-cadherin;
reduce N-cadherin, Twist, and Snail		 99
miR-34b enhance E-cadherin;
reduce vimentin, ZO1, N-cadherin, and Snail		 100
miR-200c, 205 enhance E-cadherin;
reduce ZEB1, ZEB2, and vimentin		 101
miR-200 enhance E-cadherin;
reduce N-cadherin, Snail, ZEB1, ZEB2, Slug		 102,103
miR-203 reduce N-cadherin and vimentin;
modulate Wnt signaling pathway		 104
miR-23b/27b reduce E-cadherin;
inhibit Rac1 activity		 105
a

These miRNAs are down-regulated during EMT.